Official websites use. Share sensitive information only on official, secure websites. Human Papillomavirus HPV is the most common cause of cervical cancer. Among different types of HPV, HPV16 the major strain causing this cancer and is sexually transmitted had been unnoticed for decades. Keeping in mind the multiple risk factors related with cervical cancer such as early age sexual activities, teenage pregnancies, smoking, use of oral contraceptives, having multiple sex partners, hormone replacement therapies and various other unknown factors lead to the onset of the disease.
Awareness for various diagnostic procedures such as Pap smears screening prove to be an effective way in eradicating the oncogenic potential of HPV. Human papilloma viruses HPV are small non enveloped virus containing double stranded DNA as their genetic material and are about 55 nm in size.
Their genome has three functional coding regions; E: a gene coding early viral function, L: a gene coding late viral function and LCR: a long control region which lies between E and L. They appear to show similarity with plyoma viruses and consist of about 72 capsomeres. The papilloma viruses and its viral nature were first seen in human warts in , and the first papilloma virus was isolated from a rabbit that was identified by Richard Shoppe in the year Even it was an early start for the detection of human papilloma viruses; this topic remained closed till 's.
Studies related with papilloma viruses were allowed to move forth only when cervical cancer's proximity with HPV was proved and with its increasing significance in the field of molecular virology [ 1 ].
Human papilloma virus is known to be the main reason for cervical carcinomas. Back in HPV was seen with its involvement in the successful development of cervical tumours and since then various epidemiological and biological statistics has justified this observation [ 2 ].
