Toggle navigation. Have you forgotten your login? Journal articles. Hide details. Abstract : Puberty is an important stage of development as a child's sexual and physical characteristics mature because of hormonal changes. To better understand puberty-related effects on brain development, we investigated the magnetic resonance imaging MRI data of subjects from 4 to 18years of age.
Subjects were grouped into before and during puberty groups according to their sexual maturity levels measured by the puberty scores. After onset of puberty, these volumetric changes then correlate more with sexual maturity level, as measured by the puberty score.
When normalized for brain volume, the volumes of the right HC decrease for boys; the volumes of the left HC increase for girls; and the volumes of the left and right PHC decrease for boys. These findings suggest that the rising levels of testosterone in boys and estrogen in girls might have opposite effects, especially for the HC and the PHC.
Our findings on sex-specific and sexual maturity-related volumes may be useful in better understanding the MTL developmental differences and related learning, memory, and emotion differences between boys and girls during puberty. Volumetric analysis of medial temporal lobe structures in brain development from childhood to adolescence..
NeuroImage , Elsevier, , 74C, pp. Metrics Record views. Contact support.
