MANGO is a database of genes mapped to cell types and processes that have been curated from the literature concerning adult neurogenesis. In its present state, the database is restricted to neurogenesis in the hippocampus. Although the literature contains data from several species, for the sake of uniformity, all genes in the database are reported as the mouse homologue. Each entry corresponds to a discrete effect of a gene as reported in a single study. Thus a study may report multiple effects for one gene, and several studies may report data for the same gene.
In this view mode, each individual entry in the database is visible. The columns are headed by text boxes or pull-down menus allowing you to refine the visible list of entries.
These filters are combinatorial, so that complex queries can be constructed. Type in the name of a gene, and a selector lists possible genes matching your search term.
Choose one to see all entries reporting this gene. Clicking on any one of the gene names in the table will open a new window with more information about that gene including links to the relevant pages from MGI and the NCBI Gene database. A pull-down menu allows you to search for all entries associated with each of the process or outcome categories. A pull-down menu allows you to search for all entries associated with each of the ontology terms, cell types or key markers.
Searching for a higher-level ontology term will also return data for all child terms. Results can also be limited by species in which the study was performed. Some studies using cultures derived from adult hippocampal precursor cells have been included. Type in the name of an author or the title of a reference, and a selector lists possible publications matching your search term. Select one to see all annotations extracted from this publication. Clicking on any one of the references in the table will open a new window with the NCBI PubMed record for that publication.
